HORDB

ID: hor005641
Uniprot ID: P81768
Protein name: Neurophysin 2
Gene name: AVP
Organism: Loxodonta africana (African elephant)
Family: Vasopressin/oxytocin family
Source: animal
Expression: NA
Disease: NA
Comments: NA
Taxonomy: Loxodonta (genus), Elephantidae (family), Proboscidea (order), Afrotheria (superorder), Eutheria, Theria, Mammalia (class), Amniota, Tetrapoda, Dipnotetrapodomorpha, Sarcopterygii (superclass), Euteleostomi, Teleostomi, Gnathostomata, Vertebrata, Craniata (subphylum), Chordata (phylum), Deuterostomia, Bilateria, Eumetazoa, Metazoa (kingdom), Opisthokonta, Eukaryota (superkingdom), cellular organisms
GO MF: GO:0005185 neurohypophyseal hormone activity
GO BP: GO:0007165 signal transduction
GO CC: GO:0005576 extracellular region

Sequence: AMSDMELRQCLPCGPGGKGRCFGPSICCGEELGCFVGTAEALRCQEENYLPSPCQSGQKPCGSGGRCAAAGICCYEESCVTEPECREGAGIH
Length: 92
Propeptide: AMSDMELRQCLPCGPGGKGRCFGPSICCGEELGCFVGTAEALRCQEENYLPSPCQSGQKPCGSGGRCAAAGICCYEESCVTEPECREGAGIH
Signal peptide: NA
Modification: NA
Glycosylation: NA
Mutagenesis: NA

Structure: (PDB_ID-from https://www.rcsb.org/; AlphaFold_DB_ID-from https://alphafold.ebi.ac.uk/; hordbxxxxxx_AF2.pdb was predicted structure by AlphaFold2; hordbxxxxxx_ESM.pdb was predicted structure by ESMFold)

AF-P81768-F1.pdb

hor005641_AF2.pdb

hor005641_ESM.pdb

Mass:	1116620	Formula:	C389H616N116O132S16
Absent amino acids:	W	Common amino acids:	GC
pI:	4.41	Basic residues:	8
Polar residues:	40	Hydrophobic residues:	19
Hydrophobicity:	-22.93	Boman Index:	-12582
Half-Life:	4.4 hour	Half-Life Yeast:	>20 hour
Half-Life E.Coli:	>10 hour	Aliphatic Index	47.83
Instability Index:	5862.61	Extinction Coefficient cystines:	3855
Absorbance 280nm:	42.36

PubMed ID: 7822104
Title: Amino acid sequence and properties of vasopressin-associated elephant neurophysin